The pituitary tumor causes overproduction of ACTH, which travels through the bloodstream to the adrenal glands, stimulating them to produce more cortisol than the body needs. The pituitary makes a number of hormones, including adrenocorticotropic hormone (ACTH). About 80% to 85% of Cushing's is pituitary-dependent, meaning it's triggered by a tumor on the pituitary, a pea-sized gland at the base of the brain. In dogs, Cushing's disease occurs naturally and is either pituitary-dependent or adrenal-dependent. Cortisol also helps to fight infections and maintain proper body weight and condition.īut too much cortisol weakens the immune system, leaving the body vulnerable to other diseases and infections. "Cortisol is one of the body's natural steroids," says Ann Stohlman, V.M.D., a veterinarian in FDA's Center for Veterinary Medicine, adding that a normal amount of cortisol helps the body adapt in times of stress. Cortisol is produced and stored by the adrenals, two small glands that sit on top of the kidneys. Cushing's disease results when the body produces too much of a hormone called cortisol. A visit to the vet and some diagnostic tests confirm that he has hyperadrenocorticism, commonly known as Cushing's disease or Cushing's syndrome. Plus, he's losing hair and has a pot-bellied appearance. Also, they're relatively affordable to purchase as puppies.Your nine-year old dog has been drinking a lot more lately and eating everything in sight. This mix is family-friendly, intelligent, eager to please, and easy to train. They require slightly less exercise than the original breed and can do well in smaller spaces, even if they aren't ideal apartment dogs. Since they are smaller than Boxers, they are less expensive to feed and easier to care for. If you understand the cons, there are many pros to this breed. Because the miniature Boxer sheds, it may not be suitable for those looking for a hypoallergenic dog breed. They aren't meant for owners with sedentary lifestyles or those who reside in apartments. The miniature Boxer is also a high-energy breed that requires a hands-on owner. Many " miniature " dogs have been heavily inbred, so it's not uncommon for them to develop genetic disorders or become ill at a young age, even from a reputable breeder. The breeding procedures used to create this mix are extremely controversial. Keep in mind that a particular pup might never face one of these health issues, but the possibility could be there in the gene pool, so it's good to be aware.Įvery dog breed and mix come with their pros and cons, and these are important to be aware of prior to bringing a breed into your household.
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